3099198-78-1
3099198-78-1
Chemical Structure
FXR agonist 16
- CAS No.: 3099198-78-1
- Formula:C23H32O2S
- Molecular Weight:372.56
InChIKey: UVRDEXSMJCOIMX-QNLWLWTNSA-N
SMILES: CC1(C)[C@]2([H])CC[C@]3(C)CCC[C@](C3)(SC4=C(C(OC)=O)C=CC=C4)[C@@]2([H])C1
Biological Activity: FXR agonist 16 is a FXR agonist with an EC50 of 2.2 μM. FXR agonist 16 activates FXR transcriptional activity, upregulates SHP and BSEP, and downregulates Cyp7a1. FXR agonist 16 exhibits hepatoprotective activity and reduces AST and ALT levels in free fatty acid-induced hepatocellular injury models. FXR agonist 16 can be used for the research of liver injury[1].
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FXR agonist 16 | FXR agonist 16 is a FXR agonist with an EC50 of 2.2 μM. FXR agonist 16 activates FXR transcriptional activity, upregulates SHP and BSEP, and downregulates Cyp7a1. FXR agonist 16 exhibits hepatoprotective activity and reduces AST and ALT levels in free fatty acid-induced hepatocellular injury models. FXR agonist 16 can be used for the research of liver injury. | |||||||||||||||||||||
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References
Keywords
