3107976-26-8
Chemical Structure
CRBN ligand-904
- CAS No.: 3107976-26-8
- Formula:C13H13BrN4O2
- Molecular Weight:337.17
InChIKey: ZOSAAETXMQOSLL-UHFFFAOYSA-N
SMILES: O=C1NC(CCN1C2=NN(C)C3=C2C=CC(CBr)=C3)=O
Biological Activity: CRBN ligand-904 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which is used to recruit cereblon protein. CRBN ligand-904 can be linked to a target protein ligand via a linker to form a PROTAC, such as PROTAC GSK3 degrader-1 (HY-185634)[1].
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CRBN ligand-904 | CRBN ligand-904 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which is used to recruit cereblon protein. CRBN ligand-904 can be linked to a target protein ligand via a linker to form a PROTAC, such as PROTAC GSK3 degrader-1 (HY-185634). | |||||||||||||||||||||
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Keywords