CRBN ligand-904
CRBN ligand-904 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which is used to recruit cereblon protein. CRBN ligand-904 can be linked to a target protein ligand via a linker to form a PROTAC, such as PROTAC GSK3 degrader-1 (HY-185634).
For research use only. We do not sell to patients.
- CAS No.: 3107976-26-8
- Formula: C13H13BrN4O2
- Molecular Weight:337.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cereblon |
CRBN ligand-904 can be linked to target protein ligands via a linker to form PROTACs, such as PROTAC GSK3 degrader-1 (HY-185634). PROTAC GSK3 degrader-1 selectively degrades GSK3α and GSK3β in HEK293 cells and SH-SY5Y neuroblastoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3107976-26-8
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Molecular Weight 337.17
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Formula C13H13BrN4O2
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SMILES
O=C1NC(CCN1C2=NN(C)C3=C2C=CC(CBr)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CRBN ligand-904 Related Classifications
HY-W1137162 Related Classifications
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