3108095-52-6
3108095-52-6
Chemical Structure
CTR/AMYR modulator-2
- CAS No.: 3108095-52-6
- Formula:C33H35ClF2N8O3
- Molecular Weight:665.13
InChIKey: GEQSIIOHRQAUMD-UHFFFAOYSA-N
SMILES: O=C(C1=C(CC(C)C)N=C2C(C=NN2C3CCN(C4CC(F)(C4)F)CC3)=C1C5=CC(OCC(N6CC7=NC=C(C=N7)Cl)=O)=C6C=C5)N
Biological Activity: CTR/AMYR modulator-2 (Example 107) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is ＜500 nM. CTR/AMYR modulator-2 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being ＜5000 nM. CTR/AMYR modulator-2 can be used for research on type 2 diabetes and obesity[1].
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CTR/AMYR modulator-2 | CTR/AMYR modulator-2 (Example 107) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is ＜500 nM. CTR/AMYR modulator-2 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being ＜5000 nM. CTR/AMYR modulator-2 can be used for research on type 2 diabetes and obesity. | |||||||||||||||||||||
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References
Keywords
