CTR/AMYR modulator-2
CTR/AMYR modulator-2 is a dual agonist of human amylin receptor 3 (AMY3R) and calcitonin receptor (CTR). CTR/AMYR modulator-2 activates AMY3R and CTR, stimulating Rel EC50 of cAMP production in UMUC3 cells by 4 nM and 1 nM, respectively. CTR/AMYR modulator-2 may be used in research on type 2 diabetes and obesity.
For research use only. We do not sell to patients.
- CAS No.: 3108095-52-6
- Formula: C33H35ClF2N8O3
- Molecular Weight:665.13
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
AMY3R 4 nM (EC50) |
CTR 1 nM (EC50) |
CTR/AMYR modulator‑2 (Example 107) acts as an agonist at the human amylin receptor (AMY3R) in UMUC3 cells, with a Rel EC50 of 4 nM and an Emax of 99% as determined in a 20‑point concentration‑response assay following 30 min of incubation[1].
CTR/AMYR modulator‑2 acts as an agonist at the human calcitonin receptor (CTR) in UMUC3 cells, with a Rel EC50 of 1 nM and an Emax of 88% under the same 20‑point assay conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3108095-52-6
-
Appearance Powder
-
Molecular Weight 665.13
-
Formula C33H35ClF2N8O3
-
SMILES
O=C(C1=C(CC(C)C)N=C2C(C=NN2C3CCN(C4CC(F)(C4)F)CC3)=C1C5=CC(OCC(N6CC7=NC=C(C=N7)Cl)=O)=C6C=C5)N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CTR/AMYR modulator-2 Related Classifications
HY-185107 Related Classifications
Powered by Bioz