3113145-60-8

Am-Ka12K4 Chemical Structure
3113145-60-8

Chemical Structure

Am-Ka12K4

  • CAS No.: 3113145-60-8
  • Formula:C126H255N11O5
  • Molecular Weight:2004.44

InChIKey: PKVMOSBDOJWBBQ-JMIICXCMSA-N

SMILES: CCCCCCCCCCCCN(CCCC[C@H](NC([C@H](CCCCN)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCCCCCCCCC

Biological Activity: Am-Ka12K4 is a weakly positively charged peptide-based ionizable lipid. Am-Ka12K4 induces membrane disruption under endosomal pH conditions and possesses high lipid fusion capacity. Am-Ka12K4 forms tightly packed, stable lipid nanoparticles. Am-Ka12K4 mediates in vivo mRNA delivery, exhibits inherent liver tropism, and can be modified to adjust organ tropism, enabling selective mRNA delivery to the spleen, lung, or thymus. Am-Ka12K4 is applicable to research related to repetitive mild traumatic brain injury[1][2].

Cat. No. Product Name Purity Description Pricing
HY-185985 		Am-Ka12K4 Am-Ka12K4 is a weakly positively charged peptide-based ionizable lipid. Am-Ka12K4 induces membrane disruption under endosomal pH conditions and possesses high lipid fusion capacity. Am-Ka12K4 forms tightly packed, stable lipid nanoparticles. Am-Ka12K4 mediates in vivo mRNA delivery, exhibits inherent liver tropism, and can be modified to adjust organ tropism, enabling selective mRNA delivery to the spleen, lung, or thymus. Am-Ka12K4 is applicable to research related to repetitive mild traumatic brain injury.
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