3115127-25-5
Chemical Structure
Enlicitide northern fragment 4
- CAS No.: 3115127-25-5
- Formula:C45H60FN7O16
- Molecular Weight:973.99
InChIKey: YGODFSRRGYYBPI-RHKYKNQDSA-N
SMILES: OC(C(O)=O)=O.NCCCCCCN1C(C(C(C[C@H]2C([N@]3[C@@H]([C@](OCC(NCC4=CC=CC(C[C@@H](C(N2)=O)N)=C4)=O)([H])CC3)C(N[C@@H]([C@H](O)C)C(OC(C)C)=O)=O)=O)=C1)=C5)=CC=C5F.OC(C(O)=O)=O
Biological Activity: Enlicitide northern fragment 4 is a key intermediate obtained via the retrosynthetic disconnection of Enlicitide decanoate (HY-W1126955). Enlicitide northern fragment 4 participates in the protecting-group-free biocatalytic convergent assembly of Enlicitide decanoate, an oral macrocyclic peptide PCSK9 inhibitor. Enlicitide northern fragment 4 can be used for the synthesis of Enlicitide decanoate, thereby supporting research related to hypercholesterolemia[1].
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Enlicitide northern fragment 4 | Enlicitide northern fragment 4 is a key intermediate obtained via the retrosynthetic disconnection of Enlicitide decanoate (HY-W1126955). Enlicitide northern fragment 4 participates in the protecting-group-free biocatalytic convergent assembly of Enlicitide decanoate, an oral macrocyclic peptide PCSK9 inhibitor. Enlicitide northern fragment 4 can be used for the synthesis of Enlicitide decanoate, thereby supporting research related to hypercholesterolemia. | |||||||||||||||||||||
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