3117543-71-9
3117543-71-9
Chemical Structure
JYQ-194
- CAS No.: 3117543-71-9
- Formula:C39H38FN11O8S
- Molecular Weight:839.85
InChIKey: DIDDIWKWKMYSEA-VWRCBCJMSA-N
SMILES: O=C([C@H]1CN(C#N)CC1)NC(S2)=NC3=C2CN(C(C4=C(F)C=CC(N5C=C(COCCOCCNC6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)N=N5)=C4)=O)CC3
Biological Activity: JYQ-194 is a PROTAC degrader that selectively induces PARK7 degradation by recruiting cereblon. JYQ-194 induces proteasome-dependent degradation of PARK7 in human tumor cells. JYQ-194 is applicable to research related to Parkinson's disease and cancer[1].
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JYQ-194 | 98.05% | JYQ-194 is a PROTAC degrader that selectively induces PARK7 degradation by recruiting cereblon. JYQ-194 induces proteasome-dependent degradation of PARK7 in human tumor cells. JYQ-194 is applicable to research related to Parkinson's disease and cancer. | ||||||||||||||||||||
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References
Keywords
