3120075-62-6
Chemical Structure
PROTAC TEAD degrader-3
- CAS No.: 3120075-62-6
- Formula:C54H59ClF4N8O6
- Molecular Weight:1027.54
InChIKey: BUPLMHLJEJEBJH-FEOXWKTGSA-N
SMILES: COC1=C(F)[C@@]([C@@]2=C(Cl)C(F)=CC3=C2[C@H](C)[C@@](CN[C@H]4CC[C@H](C(N5CCC(CN6CCC(C7=C(F)C(N(C)N=C8N9CCC(NC9=O)=O)=C8C=C7F)CC6)CC5)=O)CC4)(C%10=CC=CC=C%10)O3)=C(C(N)=O)C=C1
Biological Activity: PROTAC TEAD degrader-3 is a TEAD PROTAC degrader with an IC50 of < 5 nM against TEAD1, TEAD2, TEAD3 and TEAD4. PROTAC TEAD degrader-3 promotes ubiquitination and degradation of TEAD1/2/3/4. PROTAC TEAD degrader-3 can be used in cancer research[1].
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PROTAC TEAD degrader-3 | PROTAC TEAD degrader-3 is a TEAD PROTAC degrader with an IC50 of < 5 nM against TEAD1, TEAD2, TEAD3 and TEAD4. PROTAC TEAD degrader-3 promotes ubiquitination and degradation of TEAD1/2/3/4. PROTAC TEAD degrader-3 can be used in cancer research. | |||||||||||||||||||||
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Keywords