342821-66-3
342821-66-3
Chemical Structure
4-Acetylaminoantipyrine-d3
- CAS No.: 342821-66-3
- Formula:C13H12D3N3O2
- Molecular Weight:248.30
InChIKey: OIAGWXKSCXPNNZ-BMSJAHLVSA-N
SMILES: O=C1N(C2=CC=CC=C2)N(C(C)=C1NC(C([2H])([2H])[2H])=O)C
Biological Activity: 4-Acetylaminoantipyrine-d3 is the deuterium labeled 4-Acetylaminoantipyrine (HY-W268542). 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX)[1]. 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD[2]. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation[3].
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4-Acetylaminoantipyrine-d3 | 4-Acetylaminoantipyrine-d3 is the deuterium labeled 4-Acetylaminoantipyrine (HY-W268542). 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation. | |||||||||||||||||||||
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4-Acetylaminoantipyrine (Standard) | ≥98% | 4-Acetylaminoantipyrine (Standard) is the analytical standard of 4-Acetylaminoantipyrine. This product is intended for research and analytical applications. 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation. | ||||||||||||||||||||
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4-Acetylaminoantipyrine | 99.60% | 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation. | ||||||||||||||||||||
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References
- [1]. Berno CR, et al. Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. [Content Brief]
- [2]. Teng Y, et al. Insights into potentially toxic effects of 4-aminoantipyrine on the antioxidant enzyme copper-zinc superoxide dismutase. J Hazard Mater. 2013 Nov 15;262:318-24. [Content Brief]
- [3]. Teng Y, et al. The interaction between 4-aminoantipyrine and bovine serum albumin: multiple spectroscopic and molecular docking investigations. J Hazard Mater. 2011 Jun. [Content Brief]
