40106-12-5

NSC727447 Chemical Structure
40106-12-5

Chemical Structure

NSC727447

  • CAS No.: 40106-12-5
  • Formula:C10H14N2OS
  • Molecular Weight:210.30

IUPAC Name: 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide

InChIKey: LULYZYNTDPUEKK-UHFFFAOYSA-N

SMILES: O=C(C1=C(N)SC2=C1CCCCC2)N

Biological Activity: NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. NSC727447 has little activity against E. coli RNase H, but great selectivity over human Rnase H, with IC50s value of 2.0 μM, 2.5 μM, 100 μM, 10.6 μM, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-W028350 		NSC727447 95.0% NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. NSC727447 has little activity against E. coli RNase H, but great selectivity over human Rnase H, with IC50s value of 2.0 μM, 2.5 μM, 100 μM, 10.6 μM, respectively.
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