55399-93-4
55399-93-4
Chemical Structure
(2S,3R,4S)-4-Hydroxyisoleucine
Synonym(s): (2S,3R,4S)-4-Hydroxy-L-isoleucine
- CAS No.: 55399-93-4
- Formula:C6H13NO3
- Molecular Weight:147.17
IUPAC Name: (2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoic acid
InChIKey: OSCCDBFHNMXNME-YUPRTTJUSA-N
SMILES: O[C@@H](C)[C@H](C)[C@H](N)C(O)=O
Biological Activity: (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(2S,3R,4S)-4-Hydroxyisoleucine | 98.0% | (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(2S,3R,4S)-4-Hydroxyisoleucine (Standard) | ≥98% | (2S,3R,4S)-4-Hydroxyisoleucine (Standard) is the analytical standard of (2S,3R,4S)-4-Hydroxyisoleucine (HY-W010271). This product is intended for research and analytical applications. (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Shi X, et al. Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers. Sci Rep. 2017 Oct 20;7(1):13703. [Content Brief]
- [2]. Broca C, et al. 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion. Eur J Pharmacol. 2000 Mar 3;390(3):339-45. [Content Brief]
- [3]. Haeri MR, et al. Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic rats. Phytomedicine. 2012 May 15;19(7):571-4. [Content Brief]
