56739-21-0
Chemical Structure
Nitraquazone
Synonym(s): TVX 2706
- CAS No.: 56739-21-0
- Formula:C16H13N3O4
- Molecular Weight:311.29
IUPAC Name: 3-ethyl-1-(3-nitrophenyl)quinazoline-2,4(1H,3H)-dione
InChIKey: GNWCRBFQZDJFTI-UHFFFAOYSA-N
SMILES: O=C(N1CC)N(C2=CC=CC([N+]([O-])=O)=C2)C3=C(C=CC=C3)C1=O
Biological Activity: Nitraquazone (TVX 2706) is an anti-inflammatory and analgesic agent, belonging to the derivatives of Phenylbutazone (HY-B0230). Nitraquazone inhibits phosphodiesterase and enhances the elevation of intracellular cyclic adenosine monophosphate levels. Nitraquazone can be used in research related to anti-inflammation and analgesia[1][2].
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Nitraquazone | Nitraquazone (TVX 2706) is an anti-inflammatory and analgesic agent, belonging to the derivatives of Phenylbutazone (HY-B0230). Nitraquazone inhibits phosphodiesterase and enhances the elevation of intracellular cyclic adenosine monophosphate levels. Nitraquazone can be used in research related to anti-inflammation and analgesia. | |||||||||||||||||||||
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- [1]. Glaser T, et al. TVX 2706--a new phosphodiesterase inhibitor with antiinflammatory action. Biochemical characterization. Agents Actions. 1984;15(3-4):341-348. [Content Brief]
- [2]. Souness JE, et al. Proposal for pharmacologically distinct conformers of PDE4 cyclic AMP phosphodiesterases. Cell Signal. 1997;9(3-4):227-236. [Content Brief]
Keywords
