627536-09-8
Chemical Structure
SD-208
- CAS No.: 627536-09-8
- Formula:C17H10ClFN6
- Molecular Weight:352.75
IUPAC Name: 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine
InChIKey: BERLXWPRSBJFHO-UHFFFAOYSA-N
SMILES: FC1=CC=C(Cl)C=C1C2=NC3=NC=CN=C3C(NC4=CC=NC=C4)=N2
Biological Activity: SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, and > 100-fold selectivity over TGF-βRII.
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SD-208 | 99.44% | SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, and > 100-fold selectivity over TGF-βRII. | ||||||||||||||||||||
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SD-208 (GMP) | SD-208 (GMP) is SD-208 (HY-13227) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, and > 100-fold selectivity over TGF-βRII. | |||||||||||||||||||||
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SD-208 (Standard) | ≥98% | SD-208 (Standard) is the analytical standard of SD-208. This product is intended for research and analytical applications. SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, and > 100-fold selectivity over TGF-βRII. | ||||||||||||||||||||
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Keywords