680203-04-7
680203-04-7
Chemical Structure
CCR5/CXCR3-IN-1
- CAS No.: 680203-04-7
- Formula:C25H26N4O3S
- Molecular Weight:462.56
InChIKey: KCEIUECOYSVCTL-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(CN2CCN(CC2)C(C3=CC=C(C)C=C3)=O)=O)C=C(C4=CC=CC=C4)S1)N
Biological Activity: CCR5/CXCR3-IN-1 (compound 1) is a CXCR3 and CCR5 inhibitor. CCR5/CXCR3-IN-1 inhibits chemotaxis of CXCR3 and CCR5-expressing transformed cells, and does not inhibits the chemotaxis of transfected cells expressing CXCR4. CCR5/CXCR3-IN-1 can be used for the study of chronic arthritic rheumatism[1].
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CCR5/CXCR3-IN-1 | CCR5/CXCR3-IN-1 (compound 1) is a CXCR3 and CCR5 inhibitor. CCR5/CXCR3-IN-1 inhibits chemotaxis of CXCR3 and CCR5-expressing transformed cells, and does not inhibits the chemotaxis of transfected cells expressing CXCR4. CCR5/CXCR3-IN-1 can be used for the study of chronic arthritic rheumatism. | |||||||||||||||||||||
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References
Keywords
