68353-24-2
Chemical Structure
1-Methyl-2-nonyl-4(1H)-quinolone
- CAS No.: 68353-24-2
- Formula:C19H27NO
- Molecular Weight:285.42
IUPAC Name: 1-methyl-2-nonylquinolin-4(1H)-one
InChIKey: XIGBBPQAXHSVSN-UHFFFAOYSA-N
SMILES: O=C1C=C(CCCCCCCCC)N(C)C2=C1C=CC=C2
Biological Activity: 1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].
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1-Methyl-2-nonyl-4(1H)-quinolone | 1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM. | |||||||||||||||||||||
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- [1]. Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401. [Content Brief]
- [2]. Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8. [Content Brief]
Keywords