80731-10-8
Chemical Structure
D-(-)-3-Phosphoglyceric acid disodium
Synonym(s): 3-Phospho-D-glyceric acid disodium
- CAS No.: 80731-10-8
- Formula:C3H5Na2O7P
- Molecular Weight:230.02
IUPAC Name: sodium (R)-2-hydroxy-3-((hydroxyoxidophosphoryl)oxy)propanoate
InChIKey: RGCJWQYUZHTJBE-YBBRRFGFSA-L
SMILES: O=C(O[Na])[C@H](O)COP(O)(O[Na])=O
Biological Activity: D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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D-(-)-3-Phosphoglyceric acid disodium | 99.43% | D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis. | ||||||||||||||||||||
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- [1]. Yu-Qing Wu, et al. Low glucose metabolite 3-phosphoglycerate switches PHGDH. Cell Res. 2023 Nov;33(11):835-850. [Content Brief]
- [2]. Ramos ML, Justino LL, Gil VM, Burrows HD. NMR and DFT studies of the complexation of W(VI) and Mo(VI) with 3-phospho-D-glyceric and 2-phospho-D-glyceric acids. Dalton Trans. 2009;(43):9616-9624. [Content Brief]
- [3]. Faller LD, et al. Calorimetric studies of the role of magnesium ions in yeast enolase catalysis. Proc Natl Acad Sci U S A. 1974;71(4):1083-1087. [Content Brief]
