849011-39-8
Chemical Structure
Myosin-IN-1
- CAS No.: 849011-39-8
- Formula:C12H16N4OS2
- Molecular Weight:296.41
InChIKey: YHDHTDKZRCMSEQ-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CN1NC(NC(C)C)=S)SC(CC)=C2
Biological Activity: Myosin-IN-1 (compound F10) is a Myosin inhibitor that specifically targets cardiac myosin. Myosin-IN-1 stabilizes the biochemical and structural closed state of the cardiac myosin motor domain and reduces myocardial force production and calcium sensitivity in vitro. Myosin-IN-1 acts as a negative inotropic agent in isolated Langendroff-perfused rat hearts, reducing stress in isolated myofilaments and left ventricular pressure development. Myosin-IN-1 can be used in heart failure research[1].
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Myosin-IN-1 | 98.14% | Myosin-IN-1 (compound F10) is a Myosin inhibitor that specifically targets cardiac myosin. Myosin-IN-1 stabilizes the biochemical and structural closed state of the cardiac myosin motor domain and reduces myocardial force production and calcium sensitivity in vitro. Myosin-IN-1 acts as a negative inotropic agent in isolated Langendroff-perfused rat hearts, reducing stress in isolated myofilaments and left ventricular pressure development. Myosin-IN-1 can be used in heart failure research. | ||||||||||||||||||||
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Keywords
