Myosin-IN-1
Based on 1 Customer Validation
Myosin-IN-1 (compound F10) is a Myosin inhibitor that specifically targets cardiac myosin. Myosin-IN-1 stabilizes the biochemical and structural closed state of the cardiac myosin motor domain and reduces myocardial force production and calcium sensitivity in vitro. Myosin-IN-1 acts as a negative inotropic agent in isolated Langendroff-perfused rat hearts, reducing stress in isolated myofilaments and left ventricular pressure development. Myosin-IN-1 can be used in heart failure research.
For research use only. We do not sell to patients.
- Purity: 98.14%
- CAS No.: 849011-39-8
- Formula: C12H16N4OS2
- Molecular Weight:296.41
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 849011-39-8
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Appearance Solid
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Molecular Weight 296.41
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Formula C12H16N4OS2
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Color White to light yellow
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SMILES
O=C1C2=C(N=CN1NC(NC(C)C)=S)SC(CC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 350 mg/mL (1180.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3737 mL | 16.8685 mL | 33.7371 mL | 84.3426 mL |
| 5 mM | 0.6747 mL | 3.3737 mL | 6.7474 mL | 16.8685 mL | |
| 10 mM | 0.3374 mL | 1.6869 mL | 3.3737 mL | 8.4343 mL | |
| 15 mM | 0.2249 mL | 1.1246 mL | 2.2491 mL | 5.6228 mL | |
| 20 mM | 0.1687 mL | 0.8434 mL | 1.6869 mL | 4.2171 mL | |
| 25 mM | 0.1349 mL | 0.6747 mL | 1.3495 mL | 3.3737 mL | |
| 30 mM | 0.1125 mL | 0.5623 mL | 1.1246 mL | 2.8114 mL | |
| 40 mM | 0.0843 mL | 0.4217 mL | 0.8434 mL | 2.1086 mL | |
| 50 mM | 0.0675 mL | 0.3374 mL | 0.6747 mL | 1.6869 mL | |
| 60 mM | 0.0562 mL | 0.2811 mL | 0.5623 mL | 1.4057 mL | |
| 80 mM | 0.0422 mL | 0.2109 mL | 0.4217 mL | 1.0543 mL | |
| 100 mM | 0.0337 mL | 0.1687 mL | 0.3374 mL | 0.8434 mL |
Myosin-IN-1 Related Classifications
HY-163120 Related Classifications
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