870223-96-4
870223-96-4
Chemical Structure
AMG-Tie2-1
- CAS No.: 870223-96-4
- Formula:C25H20F3N5O2
- Molecular Weight:479.45
IUPAC Name: 4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide
InChIKey: ZVIWALRWYYSHSU-UHFFFAOYSA-N
SMILES: CNC1=NC(C2=CC=CN=C2OC3=C(C)C=CC(C(NC4=CC=CC(C(F)(F)F)=C4)=O)=C3)=CC=N1
Biological Activity: AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG-Tie2-1 is a VEGFR2 inhibitor with an IC50 of 3 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AMG-Tie2-1 | 99.5% | AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG-Tie2-1 is a VEGFR2 inhibitor with an IC50 of 3 nM. | ||||||||||||||||||||
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References
Keywords
