878670-61-2
878670-61-2
Chemical Structure
RDEA 806
- CAS No.: 878670-61-2
- Formula:C24H18BrClN4O3S
- Molecular Weight:557.85
IUPAC Name: 4-(2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)-3-chlorobenzoic acid
InChIKey: MPNGLQDRSJNLPL-UHFFFAOYSA-N
SMILES: ClC(C=C(C(O)=O)C=C1)=C1NC(CSC2=NN=C(Br)N2C3=CC=C(C4CC4)C5=C3C=CC=C5)=O
Biological Activity: RDEA 806 is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits potent in vitro inhibitory activity against both wild-type HIV-1 (EC50 = 3.05 nM) and NNRTI-resistant HIV-1[1].
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RDEA 806 | RDEA 806 is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits potent in vitro inhibitory activity against both wild-type HIV-1 (EC50 = 3.05 nM) and NNRTI-resistant HIV-1. | |||||||||||||||||||||
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References
Keywords
