1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. Cbl-b-IN-11

Cbl-b-IN-11 (Compound 466) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.4 nM and 6.1 nM, respectively.

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Cbl-b-IN-11

Cbl-b-IN-11 Estructura química

No. CAS : 2815225-15-9

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Descripciòn

Cbl-b-IN-11 (Compound 466) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.4 nM and 6.1 nM, respectively[1].

IC50 & Target

IC50: 6.1 nM (c-Cbl), 6.4 nM (Cbl-b)[1]

Peso molecular

602.64

Fòrmula

C31H35F5N6O

No. CAS
SMILES

O=C1C2=C(CN1C3=CC(NCC)=CC(C4(CC(F)(C4)F)CC5=NN=CN5C)=C3)C(C(F)(F)F)=CC(CNC6(CCC6)C)=C2

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Cbl-b-IN-11
Cat. No.:
HY-156767
Cantidad:
MCE Japan Authorized Agent: