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Art. -Nr.: HY-161691

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EBOV-IN-9

EBOV-IN-9 (compound 2b) is Diphyllin derivative that blocks Ebola viral entry with an EC₅₀ of 40 nM. EBOV-IN-9 against EBOV-infected monocyte-derived macrophages with an EC₅₀ of 107 nM.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₅H₂₂O₈
Molecular Weight:450.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

EBOV-IN-9 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

EBOV-IN-9 (compound 2b) is Diphyllin derivative that blocks Ebola viral entry with an EC₅₀ of 40 nM. EBOV-IN-9 against EBOV-infected monocyte-derived macrophages with an EC₅₀ of 107 nM^[1].

IC₅₀ & Target

EBOV

Alle Filovirus Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	>80 μM Compound: 2b	Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay	[PMID: 38875806]

Chemical Information

Molecular Weight 450.44
Formel C₂₅H₂₂O₈
SMILES

O=C1OCC2=C(OC3COCC3)C4=CC(OC)=C(OC)C=C4C(C5=CC=C(OCO6)C6=C5)=C12
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. lLaura M. Sanford, et al. Evaluation of Potency and Metabolic Stability of Diphyllin-derived Vacuolar-ATPase Inhibitors. European Journal of Medicinal Chemistry. 28 May 2024, 116537.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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EBOV-IN-9

Alle Filovirus Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

EBOV-IN-9 Related Classifications

HY-161691 Related Classifications