Fidaxomicin-d7
Based on 1 Customer Validation
Fidaxomicin-d7 (OPT-80-D7) is the deuterium labeled Fidaxomicin. Fidaxomicin (OPT-80), a macrocyclic RNA polymerase inhibitor, has a narrow spectrum of activity. Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 97.18%
- CAS. Nr.: 2143934-06-7
- Formel: C52H67D7Cl2O18
- Molecular Weight:1065.08
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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RNA Polymerase |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 2143934-06-7
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Unlabeled Cas 873857-62-6
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Appearance Solid
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Molecular Weight 1065.08
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Formel C52H67D7Cl2O18
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Color White to light yellow
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SMILES
C(O[C@H]1[C@H](O)[C@H](OC)[C@H](OC/C=2/C(=O)O[C@]([C@@H](C)O)(C/C=C(\C)/C=C(\C)/[C@H](O[C@H]3[C@@H](O)[C@@H](O)[C@H](OC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])=O)C(C)(C)O3)[C@@H](CC)/C=C(\C)/[C@@H](O)C/C=C/C2)[H])O[C@@H]1C)(=O)C4=C(CC)C(Cl)=C(O)C(Cl)=C4O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Poxton IR, et al. Fidaxomicin: a new macrocyclic, RNA polymerase-inhibiting antibiotic for the treatment of Clostridium difficile infections. Future Microbiol. 2010 Apr;5(4):539-48. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Fidaxomicin-d7 Related Classifications
HY-17580S Related Classifications
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