HDAC6-IN-68
HDAC6-IN-68 is an HDAC6 PROTAC ligand. HDAC6-IN-68 can be used to synthesize PROTAC HDAC6 degrader 7 (HY-179421).
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- Formel: C24H23N3O2
- Molecular Weight:385.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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HDAC6 118 nM (IC50) |
HDAC6 PROTAC contains two different ligands connected by a linker; one is an E3 ligase ligand (Thalidomide 5-fluoride) (HY-W087383), and the other is for Ligands of HDAC6 target protein (HDAC6-IN-68) (HY-179422). PROTAC exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 385.46
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Formel C24H23N3O2
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SMILES
O=C(C1=CC=C(CN2C3=CC=CC=C3C=CC4=C2C=CC=C4O)C=C1)NNCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)