10346 Results for "

Compound

" in MedChemExpress (MCE) Product Catalog:
Products (10346)

10346 Results for "Compound" in MCE Product Catalog:

806
806 Publications Verification
Art. -Nr.: HY-13418
CAS. Nr.: 1219168-18-9
Reinheit:  99.7%
Synonyms: Compound C dihydrochloride; BML-275 dihydrochloride
Forschungsgebiete:  

Cancer

Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
loading...
    loading...
81
81 Cited Publications
Art. -Nr.: HY-12071C
CAS. Nr.: 1062368-62-0
Synonyms: DM-3189 hydrochloride
LDN193189 (DM-3189) hydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva .
loading...
    loading...
80
80 Cited Publications
Art. -Nr.: HY-B0166C
CAS. Nr.: 5743-28-2
Synonyms: L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate
L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
loading...
    loading...
72
72 Cited Publications
Art. -Nr.: HY-D0924
CAS. Nr.: 210892-23-2
Synonyms: Sulfo-Cyanine5.5
Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
loading...
    loading...
69
69 Cited Publications
Art. -Nr.: HY-B1618
CAS. Nr.: 50-22-6
Synonyms: 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's Compound B
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
loading...
    loading...
52
52 Cited Publications
Art. -Nr.: HY-10320A
CAS. Nr.: 1283526-53-3
Synonyms: BIRB 796 hydrochloride
Target:  

Autophagy Raf p38 MAPK

Forschungsgebiete:  

Inflammation/Immunology

Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-α and IL-1β induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases .
loading...
    loading...
51
51 Cited Publications
Art. -Nr.: HY-111772
CAS. Nr.: 2216712-66-0
Reinheit:  99.74%
Synonyms: VX-445
Target:  

CFTR Autophagy

Forschungsgebiete:  

Inflammation/Immunology

Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface .
loading...
    loading...
50
50 Cited Publications
Art. -Nr.: HY-W250163
CAS. Nr.: 64417-72-7
Synonyms: β-DPN lithium; β-NAD lithium; β-Nicotinamide Adenine Dinucleotide lithium
NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .
loading...
    loading...
47
47 Cited Publications
Art. -Nr.: HY-N0174
CAS. Nr.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
loading...
    loading...
46
46 Cited Publications
Art. -Nr.: HY-D0821
CAS. Nr.: 146368-11-8
Synonyms: Sulfo-Cyanine5
CY5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
loading...
    loading...
36
36 Cited Publications
Art. -Nr.: HY-N0055
CAS. Nr.: 327-97-9
Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
loading...
    loading...
34
34 Cited Publications
Art. -Nr.: HY-108325A
CAS. Nr.: 96201-88-6
Synonyms: DuP785 sodium; NSC 368390 sodium
Brequinar (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
loading...
    loading...
27
27 Cited Publications
Art. -Nr.: HY-103617
CAS. Nr.: 94164-88-2
Reinheit:  99.79%
Target:  

Pyruvate Kinase

Forschungsgebiete:  

Cancer

PKM2-IN-1 (compound 3k) is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM .
loading...
    loading...
23
23 Cited Publications
Art. -Nr.: HY-N0156
CAS. Nr.: 508-02-1
Synonyms: Oleanic acid; Caryophyllin
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
loading...
    loading...
22
22 Cited Publications
Art. -Nr.: HY-B0183B
CAS. Nr.: 133039-73-3
Ellagic acid (dihydrate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
loading...
    loading...
22
22 Cited Publications
Art. -Nr.: HY-B1449
CAS. Nr.: 58-96-8
Synonyms: β-Uridine
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond .
loading...
    loading...
22
22 Cited Publications
Art. -Nr.: HY-N0519
CAS. Nr.: 20575-57-9
Synonyms: Cyclosin
Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer .
loading...
    loading...
21
21 Cited Publications
Art. -Nr.: HY-Y0649
CAS. Nr.: 7447-41-8
Synonyms: LiCl, Premium grade
Lithium chloride, 99% (LiCl, Premium grade) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
loading...
    loading...
21
21 Cited Publications
Art. -Nr.: HY-D0825
CAS. Nr.: 943298-08-6
Synonyms: Sulfo-Cyanine7
CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
loading...
    loading...
20
20 Cited Publications
Art. -Nr.: HY-W010968
CAS. Nr.: 149022-20-8
Synonyms: A-5'-P sodium hydrate; AMP sodium hydrate; Adenosine 5'-monophosphate sodium hydrate
5'-Adenylic acid (sodium hydrate) (A-5'-P (sodium hydrate); AMP (sodium hydrate); Adenosine 5'-monophosphate (sodium hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
loading...
    loading...