2216712-66-0
Chemical Structure
Elexacaftor
Synonym(s): VX-445
- CAS No.: 2216712-66-0
- Formula:C26H34F3N7O4S
- Molecular Weight:597.65
IUPAC Name: (S)-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide
InChIKey: MVRHVFSOIWFBTE-INIZCTEOSA-N
SMILES: CC1(C)C[C@H](C)CN1C2=C(C(NS(C3=CN(C)N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2
Biological Activity: Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Elexacaftor | 99.26% | Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface. | ||||||||||||||||||||
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Elexacaftor (Standard) | ≥98% | Elexacaftor (Standard) is the analytical standard of Elexacaftor. This product is intended for research and analytical applications. Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface. | ||||||||||||||||||||
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Elexacaftor-13C,d3 | Elexacaftor-13C,d3 is the deuterium labeled Elexacaftor (HY-111772). | |||||||||||||||||||||
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Elexacaftor-d3 | 98.28% | Elexacaftor-d3 (VX-445-d3) is the deuterium labeled Elexacaftor (HY-111772). | ||||||||||||||||||||
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