5743-28-2
Chemical Structure
L-Ascorbic acid calcium dihydrate
Synonym(s): L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate
- CAS No.: 5743-28-2
- Formula:C6H12Ca0.5O8
- Molecular Weight:232.19
SMILES: OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O.O.[0.5 Ca].O
Biological Activity: L-Ascorbic acid calcium dihydrate (L-Ascorbate calcium dihydrate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid calcium dihydrate inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid calcium dihydrate is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid calcium dihydrate exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
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L-Ascorbic acid calcium dihydrate | 99.3% | L-Ascorbic acid calcium dihydrate (L-Ascorbate calcium dihydrate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid calcium dihydrate inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid calcium dihydrate is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid calcium dihydrate exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. | ||||||||||||||||||||
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L-Ascorbic acid calcium dihydrate (Standard) | ≥98% | L-Ascorbic acid (calcium dihydrate) (Standard) is the analytical standard of L-Ascorbic acid (calcium dihydrate). This product is intended for research and analytical applications. L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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References
- [1]. Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35. [Content Brief]
- [2]. Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci. 2007 Nov 14;27(46):12577-83. [Content Brief]
- [3]. Aleksander Hinek, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75(3):173-82. [Content Brief]
- [4]. Sungrae Cho, et al. Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. Sci Rep. 2018 Jul 27;8(1):11372. [Content Brief]
