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Art. -Nr.: HY-N12958

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Uvarialeptone C

Uvarialeptone C (compound 3) is a NO production inhibitor (IC₅₀: 6.7 μM). Uvarialeptone C can be isolated from the extract of Cladosporium purpurogenum.

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Formel: C₂₅H₂₄O₇
Molecular Weight:436.45

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (298 KB)

Uvarialeptone C Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Uvarialeptone C (compound 3) is a NO production inhibitor (IC₅₀: 6.7 μM). Uvarialeptone C can be isolated from the extract of Cladosporium purpurogenum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	6.7 μM Compound: 3	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess reagent based analysis Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess reagent based analysis	[PMID: 38805684]
SNU1	IC₅₀	34 μM Compound: 3	Cytotoxicity against human SNU1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human SNU1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38805684]

Chemical Information

Molecular Weight 436.45
Formel C₂₅H₂₄O₇
SMILES

O=C(/C1=C(O)\C=C\C2=CC=CC=C2)[C@](CC3=CC(OC)=CC=C3O4)(OC)[C@]4(OC)CC1=O
Initial Source
- Microorganisms
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (298 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Teerapongpisan P, Monkantha T, Yimklan S, Mah SH, Gunter NV, Promnart P, Deachathai S, Maneerat T, Duangyod T, Charoensup R, Baka A, Andersen RJ, Laphookhieo S. Tetrahydroxanthene-1,3(2H)-diones and Oxidized Hexadiene Derivatives from Uvaria leptopoda and Their Biological Activities. J Nat Prod. 2024 May 28.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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