1. Cytokines
  2. Recombinant Human Endostatin (P.pastoris-expressed)

Recombinant Human Endostatin (P.pastoris-expressed)

Cat. No.: HY-P7009
Handling Instructions

Recombinant Human Endostatin (P.pastoris-expressed) is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion.

For research use only. We do not sell to patients.

Cytokines-MedChemExpress
Size Price Stock Quantity
10 μg $60 In-stock
Estimated Time of Arrival: December 31
50 μg $120 In-stock
Estimated Time of Arrival: December 31
100 μg $190 In-stock
Estimated Time of Arrival: December 31
250 μg   Get quote  

* Please select Quantity before adding items.

  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuEndostatin; Collagen alpha-1(XV) chain
Species

Human

Source

P. pastoris

Accession

P39060

Gene ID

80781

Molecular Weight

Approximately 16 kDa

AA Sequence

AHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK

Biological Activity
The ED50 is 10μg/mL as measured by Endothelial cells.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 17 mM citric-phosphate buffer, pH 6.2.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconsititution

Reconstitute the lyophilized recombinant Human Endostatin (P.pastoris-expressed) (rHuEndostatin) to 100 µg/mL using ddH2O.

Storage & Stability

Lyophilized recombinant Human Endostatin (P.pastoris-expressed) (rHuEndostatin) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Recombinant Human Endostatin is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion[1]. Recombinant Human Endostatin (rhEndostatin) shows a potent bioactivity and is capable of synergizing with CTX and DDP in suppression of tumor cell growth[2].

Documentation
References
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Product Name:
Recombinant Human Endostatin (P.pastoris-expressed)
Cat. No.:
HY-P7009
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