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Cat. No.: HY-145789

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Difluorocyclooctyne-CH2-benzoic acid

Difluorocyclooctyne-CH2-benzoic acid is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis. Difluorocyclooctyne-CH2-benzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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CAS No.: 1047997-30-7
Formula: C₁₆H₁₆F₂O₂
Molecular Weight:278.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Difluorocyclooctyne-CH2-benzoic acid Chemical Structure

CAS No.: 1047997-30-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Difluorocyclooctyne-CH2-benzoic acid is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis^[1]. Difluorocyclooctyne-CH2-benzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Chemical Information

CAS No. 1047997-30-7
Molecular Weight 278.29
Formula C₁₆H₁₆F₂O₂
SMILES

O=C(C1=CC=C(CC2CCCCC#CC2(F)F)C=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Julian A Codelli, et al. Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc. 2008 Aug 27;130(34):11486-93. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Difluorocyclooctyne-CH2-benzoic acid

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Difluorocyclooctyne-CH2-benzoic acid

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Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Difluorocyclooctyne-CH2-benzoic acid Related Classifications

HY-145789 Related Classifications

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