DL-threo-3-Hydroxyaspartic acid
Based on 1 Customer Validation
DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 4294-45-5
- Formula: C4H7NO5
- Molecular Weight:149.10
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 4294-45-5
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Appearance Solid
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Molecular Weight 149.10
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Formula C4H7NO5
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 16.67 mg/mL (111.80 mM; ultrasonic and adjust pH to 12 with 1 M NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. A Klegeris,et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78(1-2):152-61. [Content Brief]
[2]. Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24(34):7566-75. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.7069 mL | 33.5345 mL | 67.0691 mL | 167.6727 mL |
| 5 mM | 1.3414 mL | 6.7069 mL | 13.4138 mL | 33.5345 mL | |
| 10 mM | 0.6707 mL | 3.3535 mL | 6.7069 mL | 16.7673 mL | |
| 15 mM | 0.4471 mL | 2.2356 mL | 4.4713 mL | 11.1782 mL | |
| 20 mM | 0.3353 mL | 1.6767 mL | 3.3535 mL | 8.3836 mL | |
| 25 mM | 0.2683 mL | 1.3414 mL | 2.6828 mL | 6.7069 mL | |
| 30 mM | 0.2236 mL | 1.1178 mL | 2.2356 mL | 5.5891 mL | |
| 40 mM | 0.1677 mL | 0.8384 mL | 1.6767 mL | 4.1918 mL | |
| 50 mM | 0.1341 mL | 0.6707 mL | 1.3414 mL | 3.3535 mL | |
| 60 mM | 0.1118 mL | 0.5589 mL | 1.1178 mL | 2.7945 mL | |
| 80 mM | 0.0838 mL | 0.4192 mL | 0.8384 mL | 2.0959 mL | |
| 100 mM | 0.0671 mL | 0.3353 mL | 0.6707 mL | 1.6767 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.