ABT-518
ABT-518 is a matrix metalloproteinase inhibitor with anti-tumor activity. ABT-518 has potent inhibitory effects on gelatinase A and gelatinase B, which can inhibit tumor growth and metastasis.
For research use only. We do not sell to patients.
- CAS No.: 286845-00-9
- Formula: C21H22F3NO8S
- Molecular Weight:505.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
>50000 nM
Compound: 6 ABT-518
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Selective inhibition of the cellular TNF alpha release from LPS-stimulated THP-1 cells
Selective inhibition of the cellular TNF alpha release from LPS-stimulated THP-1 cells
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[PMID: 11754593] |
Chemical Information
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CAS No. 286845-00-9
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Molecular Weight 505.46
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Formula C21H22F3NO8S
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SMILES
O=CN([C@@H]([C@@H]1OC(C)(C)OC1)CS(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ABT-518 Related Classifications
HY-13546 Related Classifications
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