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Cat. No.: HY-153502

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FGFR4-IN-13

FGFR4-IN-13 (Compound 6) is a selective FGFR4 inhibitor. FGFR4-IN-13 is applicable to the research of hepatocellular carcinoma.

For research use only. We do not sell to patients.

CAS No.: 2020395-38-2
Formula: C₂₀H₂₂F₂N₄O₅
Molecular Weight:436.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

FGFR4-IN-13 Chemical Structure

CAS No.: 2020395-38-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

FGFR4-IN-13 (Compound 6) is a selective FGFR4 inhibitor. FGFR4-IN-13 is applicable to the research of hepatocellular carcinoma^[1].

IC₅₀ & Target^[1]

FGFR4

Chemical Information

CAS No. 2020395-38-2
Molecular Weight 436.42
Formula C₂₀H₂₂F₂N₄O₅
SMILES

C(OC=1C=NC(N[C@H]2[C@@H](NC(C=C)=O)COC2)=NC1)C3=C(F)C(OC)=CC(OC)=C3F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lin X, et al. Rotational Freedom, Steric Hindrance, and Protein Dynamics Explain BLU554 Selectivity for the Hinge Cysteine of FGFR4. ACS Med Chem Lett. 2019;10(8):1180-1186. Published 2019 Jul 3. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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