FmocNH-PEG3-CH2CH2NH2 hydrochloride
Based on 1 Customer Validation
FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.57%
- CAS No.: 906079-91-2
- Formula: C23H31ClN2O5
- Molecular Weight:450.96
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 906079-91-2
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Appearance Solid
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Molecular Weight 450.96
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Formula C23H31ClN2O5
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Color White to off-white
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SMILES
O=C(NCCOCCOCCOCCN)OCC1C2=C(C3=C1C=CC=C3)C=CC=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (277.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 125 mg/mL (277.19 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.2175 mL | 11.0875 mL | 22.1749 mL | 55.4373 mL |
| 5 mM | 0.4435 mL | 2.2175 mL | 4.4350 mL | 11.0875 mL | |
| 10 mM | 0.2217 mL | 1.1087 mL | 2.2175 mL | 5.5437 mL | |
| 15 mM | 0.1478 mL | 0.7392 mL | 1.4783 mL | 3.6958 mL | |
| 20 mM | 0.1109 mL | 0.5544 mL | 1.1087 mL | 2.7719 mL | |
| 25 mM | 0.0887 mL | 0.4435 mL | 0.8870 mL | 2.2175 mL | |
| 30 mM | 0.0739 mL | 0.3696 mL | 0.7392 mL | 1.8479 mL | |
| 40 mM | 0.0554 mL | 0.2772 mL | 0.5544 mL | 1.3859 mL | |
| 50 mM | 0.0443 mL | 0.2217 mL | 0.4435 mL | 1.1087 mL | |
| 60 mM | 0.0370 mL | 0.1848 mL | 0.3696 mL | 0.9240 mL | |
| 80 mM | 0.0277 mL | 0.1386 mL | 0.2772 mL | 0.6930 mL | |
| 100 mM | 0.0222 mL | 0.1109 mL | 0.2217 mL | 0.5544 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
FmocNH-PEG3-CH2CH2NH2 hydrochloride Related Classifications
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