GalNAc-NAG37 phosphoramidite
Based on 1 Customer Validation
GalNAc-NAG37 phosphoramidite is an N-acetylgalactosamine (GalNAc) derivative that acts as a ligand for the asialoglycoprotein receptor (ASGPR). GalNAc-NAG37 phosphoramidite can be used to synthesize GalNAc-siRNA and for oligonucleotide delivery.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2199491-27-3
- Formula: C80H127N10O37P
- Molecular Weight:1851.88
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2199491-27-3
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Appearance Solid
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Molecular Weight 1851.88
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Formula C80H127N10O37P
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Color White to off-white
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SMILES
CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OCCOCCNC([C@H](CCC(N[C@H](C(NCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)CCC(NCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC([C@@H]4CC[C@@H](CC4)OP(OCCC#N)N(C(C)C)C(C)C)=O)=O)NC(C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 70 mg/mL (37.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5400 mL | 2.7000 mL | 5.3999 mL | 13.4998 mL |
| 5 mM | 0.1080 mL | 0.5400 mL | 1.0800 mL | 2.7000 mL | |
| 10 mM | 0.0540 mL | 0.2700 mL | 0.5400 mL | 1.3500 mL | |
| 15 mM | 0.0360 mL | 0.1800 mL | 0.3600 mL | 0.9000 mL | |
| 20 mM | 0.0270 mL | 0.1350 mL | 0.2700 mL | 0.6750 mL | |
| 25 mM | 0.0216 mL | 0.1080 mL | 0.2160 mL | 0.5400 mL | |
| 30 mM | 0.0180 mL | 0.0900 mL | 0.1800 mL | 0.4500 mL |