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Referencia número: HY-N21955

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Merenskine

Merenskine is a chlorinated 1,2-unsaturated senecionine-type pyrrolizidine alkaloid and serves as a substrate for epoxidation reactions. Merenskine forms merepoxine N-oxide upon evaporation in ammoniated solvents, while it generates merepoxine under alkaline sample preparation conditions. Merenskine exhibits a pH-dependent transfer rate in black tea infusion, and the transfer rate decreases sharply under alkaline conditions.

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No. CAS: 96657-94-2
Fòrmula: C₁₈H₂₆ClNO₆
Peso molecular:387.86

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Merenskine Chemical Structure

No. CAS: 96657-94-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
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Actividad biológica

Descripciòn

In Vitro

Merenskine (5-100 μg/mL) and its N-oxide are pyrrolizidine alkaloids not naturally present in Jacobaea species^[1].
Merenskine undergoes significant degradation (up to 99% loss) when brewed in alkaline (pH 9) tea infusion conditions, alongside Jaconine and Merenskine N-oxide^[2].
Merenskine (2.5 ng/mL; 5 min) exhibits pH-dependent transfer from fortified black tea to infusions, with transfer rates dropping to 2% at pH 9^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 96657-94-2
Peso molecular 387.86
Fòrmula C₁₈H₂₆ClNO₆
SMILES

O=C(OC(CC1)[C@]2([H])N1CC=C2CO3)[C@@](O)(CCl)[C@H](C)[C@@H](C)[C@](O)(C)C3=O
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Cheng D, et al. The correlation between leaf-surface and leaf-tissue secondary metabolites: A case study with pyrrolizidine alkaloids in Jacobaea hybrid plants[J]. Metabolomics, 2017, 13(5): 47.

[2]. Kaltner F, Klein L M. Structural modifications of certain pyrrolizidine alkaloids during sample extraction and its impact on analytical results[J]. Food Analytical Methods, 2025, 18(6): 911-921.

[3]. Kaltner F, et al. Transfer of pyrrolizidine and tropane alkaloids from tea and herbal tea to infusions. Food chemistry. 2025 Oct 15;489:145026.

Calculators

Calculadora de molaridad

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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