PROTAC USP7 Degrader-2
PROTAC USP7 Degrader-2 (Compound D16) is an efficient and selective USP7 PROTAC degrader with a DC50 of 1.91 μM (in TE-12 cells). PROTAC USP7 Degrader-2 inhibits the migration of upper gastrointestinal tract (UGI) cancer cells and shows relatively weak anti-proliferative activity. PROTAC USP7 Degrader-2 can be used in the research of metastatic upper gastrointestinal cancer.
(Pink: USP7 ligand (HY-180826); Blue: Cereblon ligand (HY-41547); Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3056612-67-7
- Fòrmula: C42H44Cl2N8O6S
- Peso molecular:859.82
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Actividad biológica
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USP7 1.91 μM (DC50) |
Cereblon |
Chemical Information
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No. CAS 3056612-67-7
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Peso molecular 859.82
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Fòrmula C42H44Cl2N8O6S
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SMILES
CC1=C(C(C2=CC=NC3=C2SC(CN4C(C=CN(C4=O)CCCCCNC5=CC=CC6=C5C(N(C6=O)C7CCC(NC7=O)=O)=O)=O)=C3)=CC(Cl)=C1)NC8CCCNC8.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC USP7 Degrader-2 Related Classifications
HY-180793 Related Classifications
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