SPON2 - spondin 2 Gene

Homo sapiens

Also known as DIL1; DIL-1; MINDIN; M-SPONDIN

Gene ID: 10417 | Gene type: protein coding

About SPON2

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:1,166,932-1,208,844 (from NCBI)

This gene has 22 transcripts (splice variants), 192 orthologues and 3 paralogues. Broad expression in prostate (RPKM 48.4), endometrium (RPKM 37.2) and 18 other tissues.

Summary

Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SPON2 Products(3)

mRNA	Protein	Name
NM_001128325.3	NP_001121797.2	spondin-2 precursor
NM_001199021.2	NP_001185950.2	spondin-2 precursor
NM_012445.4	NP_036577.2	spondin-2 precursor

SPON2 Protein Structure

Spond_N

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

spondin-2

differentially expressed in cancerous and non-cancerous lung cells 1

Recombinant SPON2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70142	Spondin-2/SPON2 Protein, Human (HEK293, His)	AAH02707.1 (Q27-V331)	≥95%

Related Diseases

Diseases

Alias

Pharyngitis

Acute Pharyngitis	Chronic Pharyngitis
Acute Sore Throat	Chronic Sore Throat
Persistent Sore Throat	Pharyngeal Diseases
Chronic Pharyn/Nasopharyngitis	Chronic Pharyngitis And Nasopharyngitis
Inflamed Throat	Pharyngeal Disease
Pharyngeal Disorder	Pharyngitis - Acute
Sore Throat - Chronic	Acute Pharyngitis Nos
Acute Sore Throat Nos	Acute Throat Inflammation
Infective Pharyngitis	Infection Of Pharynx
Acute Infective Pharyngitis	Acute Infective Pharyngitis Nos
Acute Pharyngeal Inflammation	Inflammation Of The Throat
Throat Inflammation	Throat Infection
Putrid Pharyngitis	Pharyngeal Inflammation
Pharyngitis Nos	Chronic Throat Pain
Throat Catarrh

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13699	SPON2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SPON2	MGD	MGI:1923724
Bos taurus	SPON2	VGNC	VGNC:35228
Macaca mulatta	SPON2	VGNC	VGNC:82245
Felis catus	SPON2	VGNC	VGNC:80010
Canis familiaris	SPON2	VGNC	VGNC:59026
Rattus norvegicus	SPON2	RGD	RGD:708584
Others	SPON2	NCBI

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