CYB561D2 - cytochrome b561 family member D2 Gene

Homo sapiens (human)

Also known as 101F6; TSP10; TSCytb; XXcos-LUCA11.4

Gene ID: 11068 | Gene type: protein coding

About CYB561D2

Summary

Enables heme binding activity and transmembrane monodehydroascorbate reductase activity. Involved in ascorbate homeostasis. Predicted to be located in vesicle. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

CYB561D2 Products(1)

mRNA	Protein	Name
NM_001291284.2	NP_001278213.1	transmembrane reductase CYB561D2 isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables heme binding	IDA IDA: Inferred from direct assay	19734123	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables transmembrane monodehydroascorbate reductase activity	IDA IDA: Inferred from direct assay	23235316	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in ascorbate homeostasis	IDA IDA: Inferred from direct assay	23235316	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transmembrane reductase CYB561D2

cytochrome b561 domain-containing protein 2	putative tumor suppressor protein 101F6
transmembrane ascorbate ferrireductase	tumor suppressor cytochrome b561

CYB561D2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CYB561D2	O14569	PGRMC2	Homo sapiens	O15173	Validated Y2H	32296183
Intra	CYB561D2	O14569	PGRMC2	Homo sapiens	O15173	Y2H Array	32296183
Intra	CYB561D2	O14569	PGRMC2	Homo sapiens	O15173	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	RMDN3	Homo sapiens	Q96TC7	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	RMDN3	Homo sapiens	Q96TC7	Validated Y2H	32296183
Intra	CYB561D2	O14569	RMDN3	Homo sapiens	Q96TC7	Y2H Array	32296183
Intra	CYB561D2	O14569	ARL13B	Homo sapiens	Q3SXY8	Validated Y2H	32296183
Intra	CYB561D2	O14569	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	CYB561D2	O14569	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	GPX8	Homo sapiens	Q8TED1	Validated Y2H	32296183
Intra	CYB561D2	O14569	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	CYB561D2	O14569	PDE4A	Homo sapiens	P27815-4	Validated Y2H	32296183
Intra	CYB561D2	O14569	PDE4A	Homo sapiens	P27815-4	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	PDE4A	Homo sapiens	P27815-4	Y2H Array	32296183
Intra	CYB561D2	O14569	PTPN5	Homo sapiens	P54829	Validated Y2H	32296183
Intra	CYB561D2	O14569	PTPN5	Homo sapiens	P54829	Y2H Array	32296183
Intra	CYB561D2	O14569	PTPN5	Homo sapiens	P54829	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	TMEM154	Homo sapiens	Q6P9G4	Validated Y2H	32296183
Intra	CYB561D2	O14569	TMEM154	Homo sapiens	Q6P9G4	Y2H Array	32296183
Intra	CYB561D2	O14569	TMEM154	Homo sapiens	Q6P9G4	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	SLC18A1	Homo sapiens	P54219-3	Validated Y2H	32296183
Intra	CYB561D2	O14569	SLC18A1	Homo sapiens	P54219-3	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	SLC18A1	Homo sapiens	P54219-3	Y2H Array	32296183
Intra	CYB561D2	O14569	CLEC14A	Homo sapiens	Q86T13	Validated Y2H	32296183
Intra	CYB561D2	O14569	CLEC14A	Homo sapiens	Q86T13	Y2H Array	32296183
Intra	CYB561D2	O14569	CLEC14A	Homo sapiens	Q86T13	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
Intra	CYB561D2	O14569	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	FAM209A	Homo sapiens	Q5JX71	Validated Y2H	32296183
Intra	CYB561D2	O14569	TMEM45B	Homo sapiens	Q96B21	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	TMEM45B	Homo sapiens	Q96B21	Validated Y2H	32296183
Intra	CYB561D2	O14569	TMEM45B	Homo sapiens	Q96B21	Y2H Array	32296183
Intra	CYB561D2	O14569	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
Intra	CYB561D2	O14569	CREB3L1	Homo sapiens	Q96BA8	Validated Y2H	32296183
Intra	CYB561D2	O14569	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	COQ9	Homo sapiens	O75208	Validated Y2H	32296183
Intra	CYB561D2	O14569	COQ9	Homo sapiens	O75208	Y2H Array	32296183
Intra	CYB561D2	O14569	COQ9	Homo sapiens	O75208	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	CLDN7	Homo sapiens	O95471	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	CLDN7	Homo sapiens	O95471	Y2H Array	32296183
Intra	CYB561D2	O14569	CLDN7	Homo sapiens	O95471	Validated Y2H	32296183
Intra	CYB561D2	O14569	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	CD79A	Homo sapiens	P11912	Y2H Array	32296183
Intra	CYB561D2	O14569	CD79A	Homo sapiens	P11912	Validated Y2H	32296183
Intra	CYB561D2	O14569	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	CYB561D2	O14569	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	CYB561D2	O14569	SLC30A2	Homo sapiens	Q9BRI3	Y2H Array	32296183
Intra	CYB561D2	O14569	SLC30A2	Homo sapiens	Q9BRI3	Y2H Prey Pooling	32296183
Intra	CYB561D2	O14569	SLC30A2	Homo sapiens	Q9BRI3	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Name
Email *

	Sorry, but the email address you supplied was invalid.