Ripor2 - RHO family interacting cell polarization regulator 2 Gene
Also Known as Fam65b
Species: Mus musculus
Gene Type: protein coding
Gene ID: 193385
Summary
Enables identical protein binding activity. Involved in several processes, including auditory receptor cell stereocilium organization; cellular response to mechanical stimulus; and positive regulation of neutrophil migration. Located in stereocilium. Is expressed in several structures, including brain; heart; inner ear; liver; and lung. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 104. Orthologous to human RIPOR2 (RHO family interacting cell polarization regulator 2). [provided by Alliance of Genome Resources, Apr 2022]
Ripor2 Products (13)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080381.1 | NP_001073850.1 | rho family-interacting cell polarization regulator 2 isoform 2 |
| NM_001286100.1 | NP_001273029.1 | rho family-interacting cell polarization regulator 2 isoform 4 |
| NM_001286101.1 | NP_001273030.1 | rho family-interacting cell polarization regulator 2 isoform 5 |
| NM_001402912.1 | NP_001389841.1 | rho family-interacting cell polarization regulator 2 isoform 6 |
| NM_001402913.1 | NP_001389842.1 | rho family-interacting cell polarization regulator 2 isoform 4 |
| NM_001402914.1 | NP_001389843.1 | rho family-interacting cell polarization regulator 2 isoform 7 |
| NM_001402915.1 | NP_001389844.1 | rho family-interacting cell polarization regulator 2 isoform 8 |
| NM_001402916.1 | NP_001389845.1 | rho family-interacting cell polarization regulator 2 isoform 9 |
| NM_001402917.1 | NP_001389846.1 | rho family-interacting cell polarization regulator 2 isoform 10 |
| NM_001402918.1 | NP_001389847.1 | rho family-interacting cell polarization regulator 2 isoform 11 |
| NM_001402919.1 | NP_001389848.1 | rho family-interacting cell polarization regulator 2 isoform 12 |
| NM_029679.2 | NP_083955.1 | rho family-interacting cell polarization regulator 2 isoform 1 |
| NM_178658.5 | NP_848773.3 | rho family-interacting cell polarization regulator 2 isoform 3 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
rho family-interacting cell polarization regulator 2 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-112038A | GSK2983559 | Inhibitor | 99.49% | Phase 1 |
| HY-19764 | GSK2983559 active metabolite | Inhibitor | 98.86% | Phase 1 |
| HY-112038 | GSK2983559 free acid | Inhibitor | 99.49% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(10)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-100339 | GSK583 | Inhibitor | 99.93% | Unkown |
| HY-N0600 | Ginsenoside F3 | 99.84% | Unkown | |
| HY-111870 | PROTAC RIPK degrader-6 | Inhibitor | 99.01% | Unkown |
| HY-19761 | RIP2 kinase inhibitor 2 | Inhibitor | 99.69% | Unkown |
| HY-112907 | RIP2 Kinase Inhibitor 3 | Inhibitor | 99.76% | Unkown |
| HY-133014 | RIP2 kinase inhibitor 1 | Inhibitor | / | Unkown |
| HY-118316 | GSK223 | Inhibitor | / | Unkown |
| HY-136010 | RIP2 Kinase Inhibitor 4 | Inhibitor | / | Unkown |
| HY-147235 | PROTAC RIPK2 Degrader-1 | Inhibitor | / | Unkown |
| HY-RS12002 | RIPOR2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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