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Cat. No.: HY-184890

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RIP2K-ligand-1

RIP2K-ligand-1 is a PROTAC target protein ligand targeting RIP2K, which is applicable to research related to PROTAC synthesis. RIP2K-ligand-1 serves as the target protein ligand for PROTAC RIPK degrader-6 (HY-111870).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1346547-39-4
화학식: C₂₀H₁₉N₃O₂S₂
분자량:397.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

RIP2K-ligand-1 Chemical Structure

CAS No.: 1346547-39-4

사이즈

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재고

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

RIPK2

All RIP kinase Isoforms :

In Vitro

RIP2K-ligand-1 serves as the target protein ligand for PROTAC RIPK degrader-6 (HY-111870) (example 1), which is a Cereblon ligand-based RIP Kinase degrader^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1346547-39-4
분자량 397.51
화학식 C₂₀H₁₉N₃O₂S₂
SMILES

O=S(C(C=C1)=CC(C1=NC=C2)=C2NC3=CC(N=CS4)=C4C=C3)(C(C)(C)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Harling J D, et al. Compounds for the modulation of rip2 kinase activity: WO2017046036A1. WIPO, 2017-03-23.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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RIP2K-ligand-1

All RIP kinase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RIP2K-ligand-1 Related Classifications

HY-184890 Related Classifications