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Art. -Nr.: HY-184890

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RIP2K-ligand-1

RIP2K-ligand-1 is a PROTAC target protein ligand targeting RIP2K, which is applicable to research related to PROTAC synthesis. RIP2K-ligand-1 serves as the target protein ligand for PROTAC RIPK degrader-6 (HY-111870).

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CAS. Nr.: 1346547-39-4
Formel: C₂₀H₁₉N₃O₂S₂
Molecular Weight:397.51

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

RIP2K-ligand-1 Chemical Structure

CAS. Nr.: 1346547-39-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

RIPK2

Alle RIP kinase Isoform-spezifische Produkte anzeigen :

In Vitro

RIP2K-ligand-1 serves as the target protein ligand for PROTAC RIPK degrader-6 (HY-111870) (example 1), which is a Cereblon ligand-based RIP Kinase degrader^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1346547-39-4
Molecular Weight 397.51
Formel C₂₀H₁₉N₃O₂S₂
SMILES

O=S(C(C=C1)=CC(C1=NC=C2)=C2NC3=CC(N=CS4)=C4C=C3)(C(C)(C)C)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Harling J D, et al. Compounds for the modulation of rip2 kinase activity: WO2017046036A1. WIPO, 2017-03-23.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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RIP2K-ligand-1

Alle RIP kinase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

RIP2K-ligand-1 Related Classifications

HY-184890 Related Classifications