RIP2 kinase inhibitor 1
RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders.
For research use only. We do not sell to patients.
- CAS No.: 2380028-10-2
- Formula: C17H17N5O2S
- Molecular Weight:355.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.03 μM (RIP2)[1]
RIP2 kinase inhibitor 1 (compound 11) inhibits human whole blood (hWB; IC50=0.05 μM), activin receptor-like kinase 5 (ALK5; IC50>10 μM), VEGFR2 (IC50=7.94 μM), lymphocyte-specific protein tyrosine kinase (LCK; IC50=31.6 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2380028-10-2
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Molecular Weight 355.41
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Formula C17H17N5O2S
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SMILES
O[C@@H]1[C@H](C2)NC3=C(C(N)=O)C(C4=CC(N=CS5)=C5C=C4)=NN3C[C@H]2C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RIP2 kinase inhibitor 1 Related Classifications
HY-133014 Related Classifications
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