1. Apoptosis
  2. RIP kinase
  3. RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1 

Cat. No.: HY-133014
Handling Instructions

RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders.

For research use only. We do not sell to patients.

RIP2 kinase inhibitor 1 Chemical Structure

RIP2 kinase inhibitor 1 Chemical Structure

CAS No. : 2380028-10-2

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Description

RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders[1].

IC50 & Target

IC50: 0.03 μM (RIP2)[1]

In Vitro

RIP2 kinase inhibitor 1 (compound 11) inhibits human whole blood (hWB; IC50=0.05 μM), activin receptor-like kinase 5 (ALK5; IC50>10 μM), VEGFR2 (IC50=7.94 μM), lymphocyte-specific protein tyrosine kinase (LCK; IC50=31.6 μM)[1].

Molecular Weight

355.41

Formula

C₁₇H₁₇N₅O₂S

CAS No.

2380028-10-2

SMILES

O[[email protected]@H]1[[email protected]](C2)NC3=C(C(N)=O)C(C4=CC(N=CS5)=C5C=C4)=NN3C[[email protected]]2C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

RIP2 kinase inhibitor 1RIP kinaseReceptor-interacting protein kinasesRIPKreceptorinteractingproteinRIP2autoinflammatoryInhibitorinhibitorinhibit

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RIP2 kinase inhibitor 1
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