Trpv2 - transient receptor potential cation channel, subfamily V, member 2 Gene

Also Known as GRC; Vrl1; VRL-1; OTRPC2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22368

Summary

Enables Calcium Channel activity. Involved in positive regulation of axon extension; positive regulation of calcium ion import; and positive regulation of cold-induced thermogenesis. Located in cell body; cell surface; and growth cone. Is expressed in central nervous system; dorsal root ganglion; sensory organ; and testis. Orthologous to human TRPV2 (transient receptor potential cation channel subfamily V member 2). [provided by Alliance of Genome Resources, Apr 2022]

Trpv2 Products (5)

mRNA Protein Name
NM_001382489.1 NP_001369418.1 transient receptor potential cation channel subfamily V member 2 isoform 2
NM_001382490.1 NP_001369419.1 transient receptor potential cation channel subfamily V member 2 isoform 3
NM_001382491.1 NP_001369420.1 transient receptor potential cation channel subfamily V member 2 isoform 4
NM_001382492.1 NP_001369421.1 transient receptor potential cation channel subfamily V member 2 isoform 5
NM_011706.2 NP_035836.2 transient receptor potential cation channel subfamily V member 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
10559903 MGI
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
10559903 MGI
Biological Process GO Annotation Evidence References Source
NOT involved in apoptotic process IDA
IDA: Inferred from direct assay
20357111 MGI
involved in positive regulation of axon extension IMP
IMP: Inferred from mutant phenotype
20357111 MGI
involved in positive regulation of calcium ion import IMP
IMP: Inferred from mutant phenotype
20357111 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
26882545 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
20357111 MGI
located in axonal growth cone IDA
IDA: Inferred from direct assay
20357111 MGI
located in cell body IDA
IDA: Inferred from direct assay
20357111 MGI
located in cell surface IDA
IDA: Inferred from direct assay
20357111 MGI
located in growth cone membrane IDA
IDA: Inferred from direct assay
20357111 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
10559903 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10559903 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily V member 2

  • growth factor regulated channel

  • growth factor-regulated calcium channel

  • osm-9-like TRP channel 2

  • vanilloid receptor-like protein 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0545 Probenecid Agonist 99.94% Yes

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132222 SET2 Antagonist 99.78% Unkown
HY-157131 TRPV2-selective blocker 1 Inhibitor 99.84% Unkown
HY-182896 HKC54 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpv2 NCBI NCBI:51393