Cd226 - CD226 antigen Gene

Also Known as Pta1; DNAM1; DNAM-1; TLiSA1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 225825

Summary

Predicted to enable Integrin binding activity and protein kinase binding activity. Acts upstream of or within positive regulation of interferon-gamma production and positive regulation of natural killer cell cytokine production. Located in external side of plasma membrane. Is expressed in embryo. Orthologous to human CD226 (CD226 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd226 Products (2)

mRNA Protein Name
NM_001039149.1 NP_001034238.1 CD226 antigen isoform b
NM_178687.2 NP_848802.2 CD226 antigen isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15752754 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytokine production IDA
IDA: Inferred from direct assay
15752754 MGI
acts upstream of natural killer cell cytokine production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
acts upstream of or within positive regulation of natural killer cell cytokine production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
acts upstream of or within positive regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19648922 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD226 antigen

  • platelet and T cell activation antigen 1

Cd226 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
SPR
30591568
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
X-Ray Diffraction
30591568
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
GMS
30591568
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Cd226 Proteins

Cat. No. Product Name Accession Purity
HY-P72669 DNAM-1 Protein, Mouse (HEK293, His) Q8K4F0 (E19-P254) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02211 CD226 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16914 Cd226 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23356 Cd226 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992205 Anti-CD226 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd226 NCBI NCBI:10666