Mt1 - metallothionein 1 Gene

Also Known as Mt; Mt1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24567

Summary

Predicted to enable copper ion binding activity and zinc ion binding activity. Involved in response to cadmium ion and response to zinc ion. Predicted to be located in cytosol and lysosome. Predicted to be active in cytoplasm and nucleus. Biomarker of kidney failure; median neuropathy; and transient cerebral ischemia. Orthologous to human MT1A (metallothionein 1A). [provided by Alliance of Genome Resources, Apr 2022]

Mt1 Products (1)

mRNA Protein Name
NM_138826.4 NP_620181.1 metallothionein-1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
19938953 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
17074742 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metallothionein-1

  • MT-1

  • MT-I

  • metallothionein 1a

  • metallothionein-I

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0014 Ramelteon Agonist 99.85% Yes

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-105285 Piromelatine Agonist 99.70% Phase 3
HY-106136 TIK-301 Agonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114962 S-22153 Antagonist 99.94% Unkown
HY-101176 2-Iodomelatonin Agonist 99.04% Unkown
HY-138626 ACH-000143 Agonist 98.58% Unkown
HY-101074 UCM 608 Agonist 99.18% Unkown
HY-17038S Agomelatine-d6 Agonist 99.05% Unkown
HY-A0014S Ramelteon-d5 Agonist 99.83% Unkown
HY-17038S2 Agomelatine-d3 Agonist 98.0% Unkown
HY-107628 N-Pentanoyl 2-benzyltryptamine Antagonist 99.0% Unkown
HY-17038S1 Agomelatine-d4 Agonist / Unkown
HY-180198 UCM1400 / Unkown
HY-100940 6-Chloromelatonin Agonist / Unkown
HY-147542 Melatonin receptor agonist 1 Agonist / Unkown
HY-133112 7-Desmethyl-3-hydroxyagomelatine Agonist / Unkown
HY-131947 DH97-7 Antagonist / Unkown
HY-115304 UCM 793 Agonist / Unkown