2. UCM 608

UCM 608  (Synonyms: 2-Phenylmelatonin)

Cat. No.: HY-101074 Purity: 99.18%
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UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4.

For research use only. We do not sell to patients.

UCM 608 Chemical Structure

UCM 608 Chemical Structure

CAS No. : 151889-03-1

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Solid + Solvent
10 mM * 1 mL in DMSO
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UCM 608 Related Antibodies

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Description

UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

IC50 & Target

pKi: 10.7 (MT1)[1].
pKi: 10.4 (MT2)[1]
In Vitro

UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UCM 608 Related Antibodies
Molecular Weight

308.37

Formula

C19H20N2O2
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (324.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2429 mL 16.2143 mL 32.4286 mL
5 mM 0.6486 mL 3.2429 mL 6.4857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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=
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2429 mL 16.2143 mL 32.4286 mL 81.0714 mL
5 mM 0.6486 mL 3.2429 mL 6.4857 mL 16.2143 mL
10 mM 0.3243 mL 1.6214 mL 3.2429 mL 8.1071 mL
15 mM 0.2162 mL 1.0810 mL 2.1619 mL 5.4048 mL
20 mM 0.1621 mL 0.8107 mL 1.6214 mL 4.0536 mL
25 mM 0.1297 mL 0.6486 mL 1.2971 mL 3.2429 mL
30 mM 0.1081 mL 0.5405 mL 1.0810 mL 2.7024 mL
40 mM 0.0811 mL 0.4054 mL 0.8107 mL 2.0268 mL
50 mM 0.0649 mL 0.3243 mL 0.6486 mL 1.6214 mL
60 mM 0.0540 mL 0.2702 mL 0.5405 mL 1.3512 mL
80 mM 0.0405 mL 0.2027 mL 0.4054 mL 1.0134 mL
100 mM 0.0324 mL 0.1621 mL 0.3243 mL 0.8107 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UCM 608151889-03-12-PhenylmelatoninUCM608UCM-608Inhibitorinhibitorinhibit

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