151889-03-1
151889-03-1
Chemical Structure
UCM 608
Synonym(s): 2-Phenylmelatonin
- CAS No.: 151889-03-1
- Formula:C19H20N2O2
- Molecular Weight:308.37
IUPAC Name: N-(2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl)acetamide
InChIKey: OFCLARYYBGKCHN-UHFFFAOYSA-N
SMILES: CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=O
Biological Activity: UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].
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UCM 608 | 99.18% | UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4. | ||||||||||||||||||||
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UCM 608 (Standard) | ≥98% | UCM 608 (Standard) is the analytical standard of UCM 608 (HY-101074). This product is intended for research and analytical applications. UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4. | ||||||||||||||||||||
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References
- [1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45. [Content Brief]
- [2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.
