7-Desmethyl-3-hydroxyagomelatine
7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist.
For research use only. We do not sell to patients.
- CAS No.: 166527-00-0
- Formula: C14H15NO3
- Molecular Weight:245.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All 5-HT Receptor Isoforms
More
Biological Activity
|
MT2 |
MT1 |
5-HT2C Receptor |
Chemical Information
-
CAS No. 166527-00-0
-
Molecular Weight 245.27
-
Formula C14H15NO3
-
SMILES
CC(NCCC1=C2C=C(O)C=CC2=CC(O)=C1)=O
-
Synonyms
3-Hydroxy-7-desmethyl agomelatine
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6. [Content Brief]
[2]. Kennedy SH, et al. Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatr Dis Treat. 2007 Aug;3(4):423-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
7-Desmethyl-3-hydroxyagomelatine Related Classifications
HY-133112 Related Classifications
Powered by Bioz