CNPY4 - canopy FGF signaling regulator 4 Gene

Also Known as PRAT4B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 245812

About CNPY4

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,119,634-100,125,508 (from NCBI)

This gene has 5 transcripts (splice variants), 166 orthologues and 1 paralogue. Ubiquitous expression in endometrium (RPKM 13.2), ovary (RPKM 11.6) and 24 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Involved in positive regulation of protein localization to plasma membrane. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

CNPY4 Products (1)

mRNA Protein Name
NM_152755.2 NP_689968.1 protein canopy homolog 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
16338228 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNPY4 Protein Structure

DUF3456

DUF3456: TLR4 regulator and MIR-interacting MSAP (36 - 196)

  • 0
  • 100
  • 200
  • 248 a.a.
Protein Preferred Names Protein Names

protein canopy homolog 4

  • PRotein Associated with Tlr4

CNPY4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CNPY4 Q8N129 AIFM2 Homo sapiens Q9BRQ8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CNPY4 Proteins

Cat. No. Product Name Accession Purity
HY-P77339 CNPY4/PRAT4B Protein, Human (HEK293, His) Q8N129 (G22-L248) ≥ 85%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Lissencephaly 8

  • LIS8
Spinocerebellar Ataxia, Autosomal Recessive 24

  • SCAR24

  • Autosomal Recessive Spinocerebellar Ataxia 24

  • Spinocerebellar Ataxia, Autosomal Recessive, 24

  • Ataxia, Spinocerebellar, Autosomal Recessive, Type 24
Early Infantile Epileptic Encephalopathy

  • Early Infantile Epileptic Encephalopathy With Burst-Suppression

  • Early Infantile Epileptic Encephalopathy With Suppression Bursts

  • Eiee

  • Early Infantile Epileptic Encephalopathy With Suppression-Bursts

  • Ohtahara Syndrome

  • Encephalopathy, Epileptic, Early Infantile
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02913 CNPY4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19668 Cnpy4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26161 Cnpy4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CNPY4 RGD RGD:1307636
Felis catus CNPY4 VGNC VGNC:61033
Mus musculus CNPY4 MGD MGI:1913705
Bos taurus CNPY4 VGNC VGNC:27528
Canis familiaris CNPY4 VGNC VGNC:39425
Macaca mulatta CNPY4 VGNC VGNC:71364
Others CNPY4 NCBI